Performed

Mon-Fri

Methodology

Fluorescence in situ Hybridization

Reported

3-7 days

Synonyms

  • FISH
  • HER-2/neu
  • FFPE
  • ERBB2
  • Her2
  • Cytogenetics

Performing Lab

Cytogenetics / Cytogenomics

Specimen Type

Tumor tissue, FFPE (Formalin Fixed Paraffin Embedded)

Specimen Volume

4 unstained slides;1H&E slide

Collection Container

Sterile container

Unacceptable Conditions

Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer(R)) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.

Storage/Transport Temperature

Room temperature or refrigerated.

Stability (from collection to initiation)

Room Temperature: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Remarks

Include surgical pathology report. Provide clinical indication/ICD-10 diagnosis code for testing.

Collection Instructions

Transport sample to lab ASAP. Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport 4 slides, each with 5-micron unstained sections and 1 slide with 5-micron H&E stained section wiht the circled target area.

Special Processing Instructions After Hours

In case there is a test sample determined "STAT" by the ordering physician, genetic counselor or provider to be routed to CALM Cytogenetics and it is outside regular business hours (after hours, holidays or weekends) please contact:

NAME: Cytogenetics team

PAGER: 619-290-8698

Please be aware that ALL neonatal testing ordered for Cytogenetics is considered "STAT" as well.

Point of contact (above) will follow up on cascading down information as needed.

Thanks for your cooperation.

Reference Interval

By report

Interpretive Data

Refer to report. UCSD uses the most recent ASCO/CAP interpretation criteria for evaluating ERBB2 (HER2) status.
Ordering

Performed

Mon-Fri

Methodology

Fluorescence in situ Hybridization

Reported

3-7 days

Synonyms

  • FISH
  • HER-2/neu
  • FFPE
  • ERBB2
  • Her2
  • Cytogenetics

Performing Lab

Cytogenetics / Cytogenomics
Collection

Specimen Type

Tumor tissue, FFPE (Formalin Fixed Paraffin Embedded)

Specimen Volume

4 unstained slides;1H&E slide

Collection Container

Sterile container

Unacceptable Conditions

Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer(R)) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.

Storage/Transport Temperature

Room temperature or refrigerated.

Stability (from collection to initiation)

Room Temperature: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Remarks

Include surgical pathology report. Provide clinical indication/ICD-10 diagnosis code for testing.

Collection Instructions

Transport sample to lab ASAP. Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport 4 slides, each with 5-micron unstained sections and 1 slide with 5-micron H&E stained section wiht the circled target area.

Special Processing Instructions After Hours

In case there is a test sample determined "STAT" by the ordering physician, genetic counselor or provider to be routed to CALM Cytogenetics and it is outside regular business hours (after hours, holidays or weekends) please contact:

NAME: Cytogenetics team

PAGER: 619-290-8698

Please be aware that ALL neonatal testing ordered for Cytogenetics is considered "STAT" as well.

Point of contact (above) will follow up on cascading down information as needed.

Thanks for your cooperation.
Result Interpretation

Reference Interval

By report

Interpretive Data

Refer to report. UCSD uses the most recent ASCO/CAP interpretation criteria for evaluating ERBB2 (HER2) status.