Ordering Recommendations

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis

Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative

Establishing a quantitative baseline value for MuSK antibodies that allows comparison with future levels if weakness is worsening

Collect

Serum separator tube

Specimen Preparation

1.5 mL serum required

Storage/Transport Temperature

Store refrigerated. Ship refrigerated.

Unacceptable Conditions

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Stability (from collection to initiation)

Refrigerated (preferred) 28 days
Frozen 28 days
Ambient 72 hours

 

Minimum Requirements

1.0 mL serum

Lab Section

Send-Out Lab

Methodology

Radioimmunoassay (RIA)

Performed

Monday through Friday; 6 a.m.

Reported

3 - 10 days

Synonyms

  • MUSK AB
  • MuSK Antibody

Reference Lab Number

MUSK

Performing Laboratory Website (click below)

Mayo Medical Laboratory

Reference Interval

< or =0.02 nmol/L

Interpretive Data

A positive result, in the appropriate clinical context, confirms the diagnosis of autoimmune muscle-specific kinase myasthenia gravis.

Seropositivity justifies consideration of immunotherapy.

CPT Codes

86366

LOINC Mapping

Test ID Test Order Name Order LOINC Value
MUSK MuSK Autoantibody, S 51716-9

 

Result ID Test Result Name Result LOINC Value
64277 MuSK Autoantibody, S 51716-9

Order Type (Individual or Group)

I

Result Test ID

MUSKR

Reportable?

Y

Result Test Name

MUSCLE-SPECIFIC KINASE AB

Result Type (Individual or Group)

I

Type (Alpha or Numeric)

A

CPT Codes

86366

LOINC Mapping

Test ID Test Order Name Order LOINC Value
MUSK MuSK Autoantibody, S 51716-9

 

Result ID Test Result Name Result LOINC Value
64277 MuSK Autoantibody, S 51716-9

Pricing

Refer to Lab Account Manager. email: labservicesoutreach@urmc.rochester.edu
Specimen Requirements

Ordering Recommendations

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis

Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative

Establishing a quantitative baseline value for MuSK antibodies that allows comparison with future levels if weakness is worsening

Collect

Serum separator tube

Specimen Preparation

1.5 mL serum required

Storage/Transport Temperature

Store refrigerated. Ship refrigerated.

Unacceptable Conditions

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Stability (from collection to initiation)

Refrigerated (preferred) 28 days
Frozen 28 days
Ambient 72 hours

 

Minimum Requirements

1.0 mL serum

Testing

Lab Section

Send-Out Lab

Methodology

Radioimmunoassay (RIA)

Performed

Monday through Friday; 6 a.m.

Reported

3 - 10 days

Synonyms

  • MUSK AB
  • MuSK Antibody

Reference Lab Number

MUSK

Performing Laboratory Website (click below)

Mayo Medical Laboratory

Result Interpretation

Reference Interval

< or =0.02 nmol/L

Interpretive Data

A positive result, in the appropriate clinical context, confirms the diagnosis of autoimmune muscle-specific kinase myasthenia gravis.

Seropositivity justifies consideration of immunotherapy.

Coding

CPT Codes

86366

LOINC Mapping

Test ID Test Order Name Order LOINC Value
MUSK MuSK Autoantibody, S 51716-9

 

Result ID Test Result Name Result LOINC Value
64277 MuSK Autoantibody, S 51716-9
URM Labs Internal
Test Build

Order Type (Individual or Group)

I

Result Test ID

MUSKR

Reportable?

Y

Result Test Name

MUSCLE-SPECIFIC KINASE AB

Result Type (Individual or Group)

I

Type (Alpha or Numeric)

A

CPT Codes

86366

LOINC Mapping

Test ID Test Order Name Order LOINC Value
MUSK MuSK Autoantibody, S 51716-9

 

Result ID Test Result Name Result LOINC Value
64277 MuSK Autoantibody, S 51716-9

Pricing

Refer to Lab Account Manager. email: labservicesoutreach@urmc.rochester.edu

Important Information

Lab Section

Send-Out Lab

Restricted Test Information

RESTRICTED TEST: This test is restricted to board-certified, subspecialty trained physicians with Staff Privileges at Strong Memorial Hospital, Highland Hospital or F.F. Thompson Hospital. For exceptions: Please refer to the LDC Appeal Process.

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