Collect

Heme samples : one 4.5 mL blood in EDTA (lav top), or one 3 mL bone marrow in EDTA (min 0.5mL or >100K nucleated cells). Yellow top (ACD) Vacutainers are also acceptable.
Fresh tissue: min 0.1mL
Frozen tissue: min 100mg or 0.5cc / 0.5 cm3
Body Fluids: >200K cells

Storage/Transport Temperature

20-25°C for several hours acceptable
Fresh tissue should be sent in saline soaked gauze, a tube with saline, or tissue culture medium. 
Frozen samples should be sent on dry ice.

Unacceptable Conditions

Sample is rejected if specimen identity is in doubt.

Remarks

This test is lab-ordered only.

Stability (from collection to initiation)

Ambient: 72 hours: Refrigerated: 1 week
Fresh tissue should be sent in saline soaked gauze, a tube with saline, or tissue culture medium.  Frozen samples should be sent on dry ice.

Lab Section

Molecular Diagnositcs

Methodology

Targeted Next Generation Sequencing (NGS)

Performed

2 - 4x per week

Reported

7 - 10 working days

Synonyms

  • Heme Malignancy NGS

Performing Laboratory Website (click below)

Notes

MCMP: ABL1, ANKRD26, ASXL1, BCOR, BRAF, CALR, CBL, CEBPA, CSF3R, DDX41, DNMT3A, ETV6, EZH2, FLT3, GATA2, HRAS, IDH1, IDH2, IKZF1, JAK2, KIT, KRAS, MPL, MYD88, NF1, MPM1, NRAS, PHF6, PPM1D, PTPN11, RB1, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, TET2, TP53, U2AF1, WT1, ZRSR2

Interpretive Data

Resulted as part of Pathology report. 

CPT Codes

81450

CPT Codes

81450
Specimen Requirements

Collect

Heme samples : one 4.5 mL blood in EDTA (lav top), or one 3 mL bone marrow in EDTA (min 0.5mL or >100K nucleated cells). Yellow top (ACD) Vacutainers are also acceptable.
Fresh tissue: min 0.1mL
Frozen tissue: min 100mg or 0.5cc / 0.5 cm3
Body Fluids: >200K cells

Storage/Transport Temperature

20-25°C for several hours acceptable
Fresh tissue should be sent in saline soaked gauze, a tube with saline, or tissue culture medium. 
Frozen samples should be sent on dry ice.

Unacceptable Conditions

Sample is rejected if specimen identity is in doubt.

Remarks

This test is lab-ordered only.

Stability (from collection to initiation)

Ambient: 72 hours: Refrigerated: 1 week
Fresh tissue should be sent in saline soaked gauze, a tube with saline, or tissue culture medium.  Frozen samples should be sent on dry ice.
Testing

Lab Section

Molecular Diagnositcs

Methodology

Targeted Next Generation Sequencing (NGS)

Performed

2 - 4x per week

Reported

7 - 10 working days

Synonyms

  • Heme Malignancy NGS

Performing Laboratory Website (click below)

Notes

MCMP: ABL1, ANKRD26, ASXL1, BCOR, BRAF, CALR, CBL, CEBPA, CSF3R, DDX41, DNMT3A, ETV6, EZH2, FLT3, GATA2, HRAS, IDH1, IDH2, IKZF1, JAK2, KIT, KRAS, MPL, MYD88, NF1, MPM1, NRAS, PHF6, PPM1D, PTPN11, RB1, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, TET2, TP53, U2AF1, WT1, ZRSR2
Result Interpretation

Interpretive Data

Resulted as part of Pathology report. 
Coding

CPT Codes

81450
URM Labs Internal
Test Build

CPT Codes

81450