Notes

This test is New York DOH approved.

Collect

Blood in 3mL Lav EDTA. Collect only Mon-Fri. On Fridays, must be received to Burnet lab by 1100 

Minimum Collection Volume

2mL

Acceptable Specimen Collect Alternatives

4mL DkGr NaHep

Stability (from collection to initiation)

Room Temp 24 Hours

Shipping/Handling Instructions (Lab Use Only)

Do not spin. Critical: Room Temp

External Client Shipping and Handling

Sample must be received within 24 hours of collection.

Performing Lab

CBDI DIL:
Phone: 513-636-4685
Fax: 513-636-3861
Email: CBDILabs@cchmc.org

Units of Measure

%

Methodology

Flow Cytometry

Reported

2 days

Tests Included

Intracellular expression of Perforin and Granzyme B in NK cells and CD8+CD57+ cells.

Synonyms

  • HLH
  • Granzyme B
  • Perforin/Granzyme B By Flow

Interpretive Data

This flow cytometry assay is intended to be used as a screening test. Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient's clinical presentation suggests that the probability of a diagnosis is high.

CPT Codes

88184, 88185x4, 88187

Acceptable Specimen Collect Alternatives

4mL DkGr NaHep
Collection

Notes

This test is New York DOH approved.

Collect

Blood in 3mL Lav EDTA. Collect only Mon-Fri. On Fridays, must be received to Burnet lab by 1100 

Minimum Collection Volume

2mL

Acceptable Specimen Collect Alternatives

4mL DkGr NaHep

Stability (from collection to initiation)

Room Temp 24 Hours

Shipping/Handling Instructions (Lab Use Only)

Do not spin. Critical: Room Temp

External Client Shipping and Handling

Sample must be received within 24 hours of collection.

Performing Lab

CBDI DIL:
Phone: 513-636-4685
Fax: 513-636-3861
Email: CBDILabs@cchmc.org

Units of Measure

%
Ordering

Methodology

Flow Cytometry

Reported

2 days

Tests Included

Intracellular expression of Perforin and Granzyme B in NK cells and CD8+CD57+ cells.

Synonyms

  • HLH
  • Granzyme B
  • Perforin/Granzyme B By Flow
Result Interpretation

Interpretive Data

This flow cytometry assay is intended to be used as a screening test. Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient's clinical presentation suggests that the probability of a diagnosis is high.
Laboratory Personnel Use

CPT Codes

88184, 88185x4, 88187

Acceptable Specimen Collect Alternatives

4mL DkGr NaHep