For Constitutional Microarray SNP:  a total of 2 tubes needed; 3-4 mL of whole peripheral blood in Dark Green top Sodium Heparin tube AND 3-4 mL of whole peripheral blood in a Lavender top EDTA tube. 

For Prenatal Microarray SNP: 2 mL of whole amniotic fluid or 30-100 mg of chorionic villi in sterile transport medium - send parental samples also (a total of 2 tubes needed on EACH parent; 3-4 mL of whole peripheral blood in Dark Green top Sodium Heparin tube AND 3-4 mL of whole peripheral blood in a Lavender top EDTA tube)

For Oncology Microarray SNP:   a total of 2 tubes needed; 3-4 mL of whole bone marrow or oncology blood in Dark Green top Sodium Heparin tube AND 3-4 mL of whole bone marrow or oncology blood in a Lavender top EDTA tube. The lab should be able to perform both Oncology FISH and Oncology Chromosome Analysis in addition to the Oncology Microarray SNP with the above sample requirements - so NO additional specimen is needed for those studies if the required 2 tubes are sent.

Collection personnel MUST initial specimen container to confirm sample identity.

If DNA is sent, it MUST have been extracted in a CLIA certified laboratory.

A total of 2 tubes is needed for Constitutional or Oncology Microarray; 3-4 mL of whole bone marrow or oncology blood or peripheral blood in Dark Green top Sodium Heparin tube AND 3-4 mL of whole bone marrow or oncology blood or peripheral blood in a Lavender top EDTA tube. 

OR

2 mL of whole amniotic fluid or 30-100 mg of chorionic villi (for PRENATAL microarray)

If a lesser volume of sample listed above is sent, the laboratory will attempt to perform the test requested.  The laboratory cannot assure either a result and/or the ability to perform repeat testing and/or additional testing if the minimum volumes are not met.

ACD (Yellow) top blood tube is acceptable.

Cincinnati Children's is an Illumina Certified Service Provider (CSPro) Cincinnati Children’s Cytogenetics Laboratory is a CAP-accredited CLIA-certified clinical laboratory offering Microarray services to detect DNA copy number changes. Our knowledgeable and experienced team provides two service options for multiple sample types:

Tech Only with data generation
or
Full Service with data generation and comprehensive cytogenetic copy number data interpretation

OHC TEST ID# :   4751380

Label tubes with patient name and date of birth (DOB).

Prenatal:  For twin pregnancies, label tubes with the mother's name and "TWIN A" on one fetal sample and "TWIN B" on the second fetal sample.

Prenatal:  Protect from light.  Store at room temperature. Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Amniocentesis: Protect from light.  Store at room temperature. Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Chorionic Villus Sampling (CVS): If storing overnight, please REFRIGERATE. Ship in STERILE transport media in STERILE tubes. Tubes with media can be obtained from our lab (call 636-4474 for more information). Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Constitutional and Oncology:  Store at room temperature  / Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Cytogenetics Laboratory (513) 636-4474  /  FAX: (513) 636-4373

6 AM - 12 AM (Monday through Friday, with more limited hours on the weekend)

If the MICROARRAY : SNP sample is for PRENATAL STUDIES (from amniotic fluid or chorionic villi), there will be an additional charge added for culture of the sample (CPT code 88240).

Microarray analysis is performed using a SNP based microarray chip with over approximately 840,000 markers. This test is designed to identify chromosomal imbalances throughout the human genome including deletions, duplications, aneuploidy, and region of homozygosity. Our laboratory has established criteria for reporting abnormalities based on size, gene content, and clinical significance.

3 Weeks

FOR Constitutional MA SNP:  81229
FOR Oncology MA SNP:  81277
PRENATAL SNP needing Tissue CULTURE:  add 88240 to Constitutional MA : SNP

Please call 1-866-450-4198 for pricing or with any billing questions.