Serum is the preferred specimen. Use Gold Serum Separator Tube-Clot Activator & Gel. REMARK: Plasma is an acceptable alternative specimen in a lavender (EDTA) tube, same volume required.
Unacceptable Conditions
Do not use serum specimens that are heat-inactivated, pooled, grossly hemolyzed, or contain obvious microbial contamination. Performance has not been established for the use of cadeveric specimens or the use of boody fluids other than human serum or plasma.
Storage/Transport Temperature
For the CHOP enterprise, a total of 2-4 ml of blood (for every 2-3 HIV and Hepatitis tests ordered) should be collected and submitted at room temperature to the laboratory.
For outside clients, it is recommended that serum or plasma specimens be removed from the clot, red blood cells, or separator gel as soon as possible after collection and before shipping specimens.
Volume Required
4 ml of blood
Minimum Required
2 ml of blood
Phlebotomy Draw
Yes
Performed
Monday thru Friday
Methodology
Chemiluminescent microparticle immunoassay
Reported
Daily
Utility
The detection of HBV core IgM is an indicator of acute infection with Hepatitis B virus (HBV); can occasionally persist at low levels during chronic infection. IgM antibody to core antigen (IgM anti-HBc) is present at the onset of acute hepatitis B infection and persists for 3-12 months before declining to indetectable levels. A positive test for IgM anti-HBc is diagnostic for acute or recent HBV infection and may be the only marker present in acutely ill neonates and patients with acute fulminant HBV infection who may not have detectable HBsAg.
Synonyms
anti-HBc IgM, Hepatitis B Virus Core IgM Antibody
LIS Mnemonic
HBVCOREIGM
Available STAT
No
Interp Data
The presence of HBV core IgM antibody is indicative of a recent acute infection with HBV
Reference Ranges
Negative or nonreactive for Hepatitis B Virus (HBV) core IgM antibody
CPT Codes
86705
Collection
Collect
Serum is the preferred specimen. Use Gold Serum Separator Tube-Clot Activator & Gel. REMARK: Plasma is an acceptable alternative specimen in a lavender (EDTA) tube, same volume required.
Unacceptable Conditions
Do not use serum specimens that are heat-inactivated, pooled, grossly hemolyzed, or contain obvious microbial contamination. Performance has not been established for the use of cadeveric specimens or the use of boody fluids other than human serum or plasma.
Storage/Transport Temperature
For the CHOP enterprise, a total of 2-4 ml of blood (for every 2-3 HIV and Hepatitis tests ordered) should be collected and submitted at room temperature to the laboratory.
For outside clients, it is recommended that serum or plasma specimens be removed from the clot, red blood cells, or separator gel as soon as possible after collection and before shipping specimens.
Volume Required
4 ml of blood
Minimum Required
2 ml of blood
Phlebotomy Draw
Yes
Ordering
Performed
Monday thru Friday
Methodology
Chemiluminescent microparticle immunoassay
Reported
Daily
Utility
The detection of HBV core IgM is an indicator of acute infection with Hepatitis B virus (HBV); can occasionally persist at low levels during chronic infection. IgM antibody to core antigen (IgM anti-HBc) is present at the onset of acute hepatitis B infection and persists for 3-12 months before declining to indetectable levels. A positive test for IgM anti-HBc is diagnostic for acute or recent HBV infection and may be the only marker present in acutely ill neonates and patients with acute fulminant HBV infection who may not have detectable HBsAg.
Synonyms
anti-HBc IgM, Hepatitis B Virus Core IgM Antibody
LIS Mnemonic
HBVCOREIGM
Available STAT
No
Result Interpretation
Interp Data
The presence of HBV core IgM antibody is indicative of a recent acute infection with HBV
Reference Ranges
Negative or nonreactive for Hepatitis B Virus (HBV) core IgM antibody
