Purpose

This test reflexes to FT3, FT4, and/or TPO as indicated.  All possible reflexed tests are based on the results of the reflex algorithm.  

Collect

Gold top Serum Separator Tube (SST)

Optimum volume - 6.0 mL
Minimum volume - 2.0 mL

Specimen Preparation

Allow sample to clot for 20 minutes prior to centrifuging

Storage/Transport Temperature

Refrigerated (2-8oC)

Stability (from collection to initiation)

After separation of cells:  Ambient - 8 hrs.
                                        Refrigerated - 72 hrs.

Cerner Orderable(s)

TSH Cascade Adult

Performed

TSH and FT4 - performed at all BayCare Hospital Laboratories
FT3 - Performed at Morton Plant Hospital, St. Joseph's Hospital
TPO - Performed at Morton Plant Hospital, St. Joseph's Hospital, St. Anthony's Hospital

24/7

Methodology

Quantitative Chemiluminescent Immunoassay

Reference Interval

Reference Range:

TSH:  0.358 - 3.740 uIU/mL
T4 Free:  0.76 - 1.46 ng/dL
T3 Free:  2.18 - 3.98 pg/mL
TPO:  0 - 60 unit/mL

 

Interpretive Data

Low TSH + High FT4 = Hyperthyroidism
Low TSH + Low FT4 = Secondary Hypothyroidism - severe illness
Low TSH/Normal FT4 + Low FT3 = Secondary Hypothyroidism - severe illness
Low TSH/Normal FT4 + Normal FT3 = Subclinical Hyperthyroidism - severe illness
Low TSH/Normal FT4 + High FT3 = Thyrotoxicosis

High TSH + Low FT4 = Hypothyroidism
High TSH + High FT4 = TSH Secreting Tumor
High TSH/Normal FT4 + Negative TPO = Subclinical Hypothyroidism - severe disease
High TSH/Normal FT4 + Positive TPO = Subclinical Hypothyroidism
Collection

Purpose

This test reflexes to FT3, FT4, and/or TPO as indicated.  All possible reflexed tests are based on the results of the reflex algorithm.  

Collect

Gold top Serum Separator Tube (SST)

Optimum volume - 6.0 mL
Minimum volume - 2.0 mL

Specimen Preparation

Allow sample to clot for 20 minutes prior to centrifuging

Storage/Transport Temperature

Refrigerated (2-8oC)

Stability (from collection to initiation)

After separation of cells:  Ambient - 8 hrs.
                                        Refrigerated - 72 hrs.
Ordering

Cerner Orderable(s)

TSH Cascade Adult

Performed

TSH and FT4 - performed at all BayCare Hospital Laboratories
FT3 - Performed at Morton Plant Hospital, St. Joseph's Hospital
TPO - Performed at Morton Plant Hospital, St. Joseph's Hospital, St. Anthony's Hospital

24/7

Methodology

Quantitative Chemiluminescent Immunoassay
Result Interpretation

Reference Interval

Reference Range:

TSH:  0.358 - 3.740 uIU/mL
T4 Free:  0.76 - 1.46 ng/dL
T3 Free:  2.18 - 3.98 pg/mL
TPO:  0 - 60 unit/mL

 

Interpretive Data

Low TSH + High FT4 = Hyperthyroidism
Low TSH + Low FT4 = Secondary Hypothyroidism - severe illness
Low TSH/Normal FT4 + Low FT3 = Secondary Hypothyroidism - severe illness
Low TSH/Normal FT4 + Normal FT3 = Subclinical Hyperthyroidism - severe illness
Low TSH/Normal FT4 + High FT3 = Thyrotoxicosis

High TSH + Low FT4 = Hypothyroidism
High TSH + High FT4 = TSH Secreting Tumor
High TSH/Normal FT4 + Negative TPO = Subclinical Hypothyroidism - severe disease
High TSH/Normal FT4 + Positive TPO = Subclinical Hypothyroidism
Administrative