Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
Synonyms
SNP array amniocentesis
SNP array CVS
SNP array chorionic villus sample
ACGHT
Array CGH Tissue or Products of Conception
Sample Type
Tissue or POC
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Collect
Sterile centrifuge tube with transport media provided by lab, Hanks balanced salt solution or RPMI with antibiotics
Amount to Collect
1 cc (Cubic centimeter) or 20 mg tissue
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Remarks
Insurance pre-authorization required for outpatients
Label tube with type of tissue being submitted
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months . Microarray will be run upon insurance authorization approval within 6 months.
Stability (from collection to initiation)
48 hours at Room temperature
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Test Code
SNPAT
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics
For questions, contact the microarray laboratory at 514-8964
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Stability (from collection to initiation)
48 hours at Room temperature
Additional Information
Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
CPT Codes
81229, 88233
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply
LDT or Modified FDA
Yes
Available Stat
No
Test Code
SNPAT
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Remarks
Insurance pre-authorization required for outpatients
Label tube with type of tissue being submitted
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months . Microarray will be run upon insurance authorization approval within 6 months.
Collect
Sterile centrifuge tube with transport media provided by lab, Hanks balanced salt solution or RPMI with antibiotics
Amount to Collect
1 cc (Cubic centimeter) or 20 mg tissue
Sample Type
Tissue or POC
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics
For questions, contact the microarray laboratory at 514-8964
Synonyms
SNP array amniocentesis
SNP array CVS
SNP array chorionic villus sample
ACGHT
Array CGH Tissue or Products of Conception
Stability (from collection to initiation)
48 hours at Room temperature
Reported
7-21 days
Additional Information
Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
CPT Codes
81229, 88233
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply
LDT or Modified FDA
Yes
Ordering
Available Stat
No
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Reported
7-21 days
Additional Information
Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
Synonyms
SNP array amniocentesis
SNP array CVS
SNP array chorionic villus sample
ACGHT
Array CGH Tissue or Products of Conception
Collection
Sample Type
Tissue or POC
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Collect
Sterile centrifuge tube with transport media provided by lab, Hanks balanced salt solution or RPMI with antibiotics
Amount to Collect
1 cc (Cubic centimeter) or 20 mg tissue
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Remarks
Insurance pre-authorization required for outpatients
Label tube with type of tissue being submitted
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months . Microarray will be run upon insurance authorization approval within 6 months.
Stability (from collection to initiation)
48 hours at Room temperature
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Processing
Test Code
SNPAT
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics
For questions, contact the microarray laboratory at 514-8964
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Stability (from collection to initiation)
48 hours at Room temperature
Result Interpretation
Additional Information
Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
Administrative
CPT Codes
81229, 88233
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply
LDT or Modified FDA
Yes
Complete View
Available Stat
No
Test Code
SNPAT
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Remarks
Insurance pre-authorization required for outpatients
Label tube with type of tissue being submitted
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months . Microarray will be run upon insurance authorization approval within 6 months.
Collect
Sterile centrifuge tube with transport media provided by lab, Hanks balanced salt solution or RPMI with antibiotics
Amount to Collect
1 cc (Cubic centimeter) or 20 mg tissue
Sample Type
Tissue or POC
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Preferred Volume
1 cc (Cubic centimeter) or 20 mg tissue
Minimum Volume
0.3 cc (Cubic centimeter) or 15 mg tissue
Unacceptable Conditions
Leaking, contaminated, frozen or mislabeled tube(s)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics
For questions, contact the microarray laboratory at 514-8964
Synonyms
SNP array amniocentesis
SNP array CVS
SNP array chorionic villus sample
ACGHT
Array CGH Tissue or Products of Conception
Stability (from collection to initiation)
48 hours at Room temperature
Reported
7-21 days
Additional Information
Limitations Genomic aberrations that may not be detected by SNP array assay include: - Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication. - Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy - Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array - Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination)
The lab will charge a tissue culture setup fees (TCAFCV) if SNP microarray is ordered without chromosomes studies
The lab will charge a tissue culture setup fees (TCPOC) if SNP microarray is ordered without chromosome studies
CPT Codes
81229, 88233
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply
