Yes, if not ordered by Genetics, Neurology or Neonatal Intensive Care Unit faculty or fellows. Requests on inpatients require approval from
Cytogenetics/Array staff.
Available Stat
No
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Reported
10-21 days
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
Synonyms
SNP array blood
Sample Type
EDTA or heparinized whole blood
Peripheral blood specimen requested. Please contact the lab at 415-353-4844 or Cyto-Mgr@ucsfmedctr.org to request approval of an alternative specimen type, if necessary.
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Collect
Lavender top preferred , Dark green top acceptable
Amount to Collect
Adult: 5 mL blood
Infant/Child: 3 mL blood
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Remarks
Insurance pre-authorization required for outpatients
Do not collect sample in lithium heparin (Lt. Green top).
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months. Microarray will be run upon insurance authorization approval within 6 months.
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Test Code
SNPAB
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics.
For questions, contact the microarray laboratory at 514-8964.
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
CPT Codes
81229
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply.
LDT or Modified FDA
Yes
Approval Required
Yes, if not ordered by Genetics, Neurology or Neonatal Intensive Care Unit faculty or fellows. Requests on inpatients require approval from
Cytogenetics/Array staff.
Available Stat
No
Test Code
SNPAB
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Remarks
Insurance pre-authorization required for outpatients
Do not collect sample in lithium heparin (Lt. Green top).
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months. Microarray will be run upon insurance authorization approval within 6 months.
Collect
Lavender top preferred , Dark green top acceptable
Amount to Collect
Adult: 5 mL blood
Infant/Child: 3 mL blood
Sample Type
EDTA or heparinized whole blood
Peripheral blood specimen requested. Please contact the lab at 415-353-4844 or Cyto-Mgr@ucsfmedctr.org to request approval of an alternative specimen type, if necessary.
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics.
For questions, contact the microarray laboratory at 514-8964.
Synonyms
SNP array blood
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Reported
10-21 days
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
CPT Codes
81229
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply.
LDT or Modified FDA
Yes
Ordering
Approval Required
Yes, if not ordered by Genetics, Neurology or Neonatal Intensive Care Unit faculty or fellows. Requests on inpatients require approval from
Cytogenetics/Array staff.
Available Stat
No
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Reported
10-21 days
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
Synonyms
SNP array blood
Collection
Sample Type
EDTA or heparinized whole blood
Peripheral blood specimen requested. Please contact the lab at 415-353-4844 or Cyto-Mgr@ucsfmedctr.org to request approval of an alternative specimen type, if necessary.
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Collect
Lavender top preferred , Dark green top acceptable
Amount to Collect
Adult: 5 mL blood
Infant/Child: 3 mL blood
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Remarks
Insurance pre-authorization required for outpatients
Do not collect sample in lithium heparin (Lt. Green top).
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months. Microarray will be run upon insurance authorization approval within 6 months.
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Processing
Test Code
SNPAB
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics.
For questions, contact the microarray laboratory at 514-8964.
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Result Interpretation
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
Administrative
CPT Codes
81229
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply.
LDT or Modified FDA
Yes
Complete View
Approval Required
Yes, if not ordered by Genetics, Neurology or Neonatal Intensive Care Unit faculty or fellows. Requests on inpatients require approval from
Cytogenetics/Array staff.
Available Stat
No
Test Code
SNPAB
Performing Lab
Medical Genomics - Cytogenetics (Microarray)
Methodology
GDA SNP Array
Remarks
Insurance pre-authorization required for outpatients
Do not collect sample in lithium heparin (Lt. Green top).
Transport sample at room temperature as soon as possible to lab. If transport is delayed refrigerate sample.
Without insurance pre -authorization, the lab will change the order to SNP microarray Processing, Extraction and Storage and hold DNA for six months. Microarray will be run upon insurance authorization approval within 6 months.
Collect
Lavender top preferred , Dark green top acceptable
Amount to Collect
Adult: 5 mL blood
Infant/Child: 3 mL blood
Sample Type
EDTA or heparinized whole blood
Peripheral blood specimen requested. Please contact the lab at 415-353-4844 or Cyto-Mgr@ucsfmedctr.org to request approval of an alternative specimen type, if necessary.
Cytogenetics laboratory only accepts genomic DNA samples for clinical microarray testing when they are extracted in a CLIA-certified laboratory and meet the lab requirement, including >=500 ng DNA with a concentration >=50ng/uL and A260/280 ratio >=1.8. Electrophoresis gel image and/or DNA integrity related information should also be provided to the lab. Acceptance of any extracted gDNA sample should be approved by the lab director. Contact Cytogenetics 514-8964.
Preferred Volume
Adult: 5 mL blood
Infant/Child: 3 mL blood
Extracted DNA: 10 micrograms
Minimum Volume
Adult: 2 mL blood
Infant/Child: 2 mL blood
Extracted DNA: 10 micrograms
Unacceptable Conditions
Insufficient volume, unlabeled tubes, clotted samples, samples received in Lithium-heparin (Lt. Green top) tubes.
Specimen Preparation
Refrigerate samples DO NOT CENTRIFUGE OR FREEZE. Transport asap to China Basin Cytogenetics.
For questions, contact the microarray laboratory at 514-8964.
Synonyms
SNP array blood
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 2 weeks.
Reported
10-21 days
Additional Information
Limitations
Genomic aberrations that may not be detected by SNP array assay include:
- Balanced rearrangement (i.e. balanced translocation, insertion or inversion) and tetraploidy resulted from endoduplication.
- Low level (<30%) mosaicism for unbalanced rearrangements and aneuploidy.
- Nucleotide sequence changes (i.e. point mutation or small insertion/deletion below the level of detection or cut-off thresholds) Imbalances of regions not represented on the array.
- Genomic changes in mixed samples (i.e. prenatal samples with maternal cell contamination).
CPT Codes
81229
Note: Additional charges for MCC studies when necessary, culture set-up fees may apply.
