Available Stat

No

Performing Lab

Quest

Methodology

Spectrometry

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

Synonyms

  • Lactase deficiency
  • palatinase deficiency
  • sucrase deficiency
  • maltase deficiency

Sample Type

Small bowel biopsy

Collect

Small bowel biopsy

Amount to Collect

5 mg

Preferred Volume

5 mg

Minimum Volume

2 mg

Remarks

Do not place tissue on gauze or filter paper; do not add saline or allow contact with support, preservatives or embedding material. Transport immediately to laboratory.

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection

Test Code

DSCS

Sendout

Yes

Performing Lab

Quest

Specimen Preparation

Specimen must be kept frozen and stored at -70C. Do not thaw. Deliver to China Basin on dry ice.

Preferred Volume

5 mg

Minimum Volume

2 mg

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection

Units

µM glucose generated/min/ g protein

Reference Interval

Lactase: 15.0-45.5 µM gluc/min/g prot
Maltase: 25-69.9 µM gluc/min/g prot
Palatinase: 100-224.4 µM gluc/min/g prot
Sucrase: 5-26.3 µM gluc/min/g prot

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

CPT Codes

84311-90 x4

LOINC Codes

1942-2

Available Stat

No

Test Code

DSCS

Performing Lab

Quest

Sendout

Yes

Methodology

Spectrometry

Remarks

Do not place tissue on gauze or filter paper; do not add saline or allow contact with support, preservatives or embedding material. Transport immediately to laboratory.

Collect

Small bowel biopsy

Amount to Collect

5 mg

Sample Type

Small bowel biopsy

Preferred Volume

5 mg

Minimum Volume

2 mg

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection

Specimen Preparation

Specimen must be kept frozen and stored at -70C. Do not thaw. Deliver to China Basin on dry ice.

Units

µM glucose generated/min/ g protein

Reference Interval

Lactase: 15.0-45.5 µM gluc/min/g prot
Maltase: 25-69.9 µM gluc/min/g prot
Palatinase: 100-224.4 µM gluc/min/g prot
Sucrase: 5-26.3 µM gluc/min/g prot

Synonyms

  • Lactase deficiency
  • palatinase deficiency
  • sucrase deficiency
  • maltase deficiency

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

CPT Codes

84311-90 x4

LOINC Codes

1942-2
Ordering

Available Stat

No

Performing Lab

Quest

Methodology

Spectrometry

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

Synonyms

  • Lactase deficiency
  • palatinase deficiency
  • sucrase deficiency
  • maltase deficiency
Collection

Sample Type

Small bowel biopsy

Collect

Small bowel biopsy

Amount to Collect

5 mg

Preferred Volume

5 mg

Minimum Volume

2 mg

Remarks

Do not place tissue on gauze or filter paper; do not add saline or allow contact with support, preservatives or embedding material. Transport immediately to laboratory.

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection
Processing

Test Code

DSCS

Sendout

Yes

Performing Lab

Quest

Specimen Preparation

Specimen must be kept frozen and stored at -70C. Do not thaw. Deliver to China Basin on dry ice.

Preferred Volume

5 mg

Minimum Volume

2 mg

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection
Result Interpretation

Units

µM glucose generated/min/ g protein

Reference Interval

Lactase: 15.0-45.5 µM gluc/min/g prot
Maltase: 25-69.9 µM gluc/min/g prot
Palatinase: 100-224.4 µM gluc/min/g prot
Sucrase: 5-26.3 µM gluc/min/g prot

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.
Administrative

CPT Codes

84311-90 x4

LOINC Codes

1942-2
Complete View

Available Stat

No

Test Code

DSCS

Performing Lab

Quest

Sendout

Yes

Methodology

Spectrometry

Remarks

Do not place tissue on gauze or filter paper; do not add saline or allow contact with support, preservatives or embedding material. Transport immediately to laboratory.

Collect

Small bowel biopsy

Amount to Collect

5 mg

Sample Type

Small bowel biopsy

Preferred Volume

5 mg

Minimum Volume

2 mg

Unacceptable Conditions

Sample submitted improperly. Delivered to laboratory > 30 minutes after collection

Specimen Preparation

Specimen must be kept frozen and stored at -70C. Do not thaw. Deliver to China Basin on dry ice.

Units

µM glucose generated/min/ g protein

Reference Interval

Lactase: 15.0-45.5 µM gluc/min/g prot
Maltase: 25-69.9 µM gluc/min/g prot
Palatinase: 100-224.4 µM gluc/min/g prot
Sucrase: 5-26.3 µM gluc/min/g prot

Synonyms

  • Lactase deficiency
  • palatinase deficiency
  • sucrase deficiency
  • maltase deficiency

Additional Information

Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.

CPT Codes

84311-90 x4

LOINC Codes

1942-2