Approval Required

Yes, for inpatient orders.

Available Stat

No

Performing Lab

Adaptive Biotechnologies

Methodology

PCR and next-generation sequencing

Reported

7 days for fresh specimens; 14 days for archived specimens

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.

Synonyms

  • Molecular Minimal residual disease testing
  • MRD
  • ClonoSight
  • LymphoSight

Sample Type

EDTA anticoagulated blood or bone marrow

Collect

Lavender top

Amount to Collect

Blood: 10 mL
Bone marrow: 3 mL

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Remarks

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

Due to limited samle stability, collect samples Monday-Friday only and send via FedEx overnight, avoiding holidays. Samples are accepted by Adaptive Biotechnologies Monday through Saturday from 8AM to 5PM PT.

See Adaptive Biotechnologies website for additional specimen requirements.

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C

Test Code

MOLT

Sendout

Yes

Performing Lab

Adaptive Biotechnologies

Specimen Preparation

Keep samples at room temperature. Forward to CB at room temperature.

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.

Approval Required

Yes, for inpatient orders.

Available Stat

No

Test Code

MOLT

Performing Lab

Adaptive Biotechnologies

Sendout

Yes

Methodology

PCR and next-generation sequencing

Remarks

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

Due to limited samle stability, collect samples Monday-Friday only and send via FedEx overnight, avoiding holidays. Samples are accepted by Adaptive Biotechnologies Monday through Saturday from 8AM to 5PM PT.

See Adaptive Biotechnologies website for additional specimen requirements.

Collect

Lavender top

Amount to Collect

Blood: 10 mL
Bone marrow: 3 mL

Sample Type

EDTA anticoagulated blood or bone marrow

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Specimen Preparation

Keep samples at room temperature. Forward to CB at room temperature.

Synonyms

  • Molecular Minimal residual disease testing
  • MRD
  • ClonoSight
  • LymphoSight

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C

Reported

7 days for fresh specimens; 14 days for archived specimens

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.
Ordering

Approval Required

Yes, for inpatient orders.

Available Stat

No

Performing Lab

Adaptive Biotechnologies

Methodology

PCR and next-generation sequencing

Reported

7 days for fresh specimens; 14 days for archived specimens

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.

Synonyms

  • Molecular Minimal residual disease testing
  • MRD
  • ClonoSight
  • LymphoSight
Collection

Sample Type

EDTA anticoagulated blood or bone marrow

Collect

Lavender top

Amount to Collect

Blood: 10 mL
Bone marrow: 3 mL

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Remarks

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

Due to limited samle stability, collect samples Monday-Friday only and send via FedEx overnight, avoiding holidays. Samples are accepted by Adaptive Biotechnologies Monday through Saturday from 8AM to 5PM PT.

See Adaptive Biotechnologies website for additional specimen requirements.

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C
Processing

Test Code

MOLT

Sendout

Yes

Performing Lab

Adaptive Biotechnologies

Specimen Preparation

Keep samples at room temperature. Forward to CB at room temperature.

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C
Result Interpretation

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.
Administrative
Complete View

Approval Required

Yes, for inpatient orders.

Available Stat

No

Test Code

MOLT

Performing Lab

Adaptive Biotechnologies

Sendout

Yes

Methodology

PCR and next-generation sequencing

Remarks

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

Due to limited samle stability, collect samples Monday-Friday only and send via FedEx overnight, avoiding holidays. Samples are accepted by Adaptive Biotechnologies Monday through Saturday from 8AM to 5PM PT.

See Adaptive Biotechnologies website for additional specimen requirements.

Collect

Lavender top

Amount to Collect

Blood: 10 mL
Bone marrow: 3 mL

Sample Type

EDTA anticoagulated blood or bone marrow

Preferred Volume

Blood: 10 mL
Bone marrow: 3 mL

Minimum Volume

Blood: 10 mL
Bone marrow: 3 mL

Specimen Preparation

Keep samples at room temperature. Forward to CB at room temperature.

Synonyms

  • Molecular Minimal residual disease testing
  • MRD
  • ClonoSight
  • LymphoSight

Stability (from collection to initiation)

4 days at room temperature
7 days at 4C

Reported

7 days for fresh specimens; 14 days for archived specimens

Additional Information

The previous lab (Sequenta; South San Francisco) that performed the ClonoSight test was purchased by Adaptive Biotechnologies (Seattle) in May of 2015 and is no longer accepting samples. The ClonoSight test has been replaced by the ClonoSeq assay, which is the name of a similar test that Adaptive Biotechnologies offers. These assays have been shown to be highly concordant.

All samples for clonoSEQ testing should be sent to Adaptive Biotechnologies in Seattle, WA.

For patients who were originally evaluated (had malignant clones identified) using Sequenta's ClonoSight assay, additional steps may be required prior to continuing with MRD testing on the Adaptive Biotechnologies clonoSEQ assay. It is imperative that the sendout lab be notified if a patient falls into this category so that they can work with Adaptive to transition the patient's testing to clonoSEQ.