Pediatric AML FISH panel

PAML, BPAML

Available Stat

No

Performing Lab

Cytogenetics

Performed

Mon - Fri, 9AM - 5PM

Methodology

FISH

Reported

7-14 days

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 

Reflex Testing

An  interpretation of this test by a laboratory physician will automatically be performed and billed for separately.

Synonyms

  • PAML
  • BPAML

Sample Type

Blood or bone marrow

Collect

Blood or bone marrow aspirate: Dark green top
Bone marrow core: Sterile container with medium

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Stability (from collection to initiation)

Room temperature: 2 days

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.

Test Code

Blood: BPAML
Bone marrow: PAML

Performing Lab

Cytogenetics

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.

Stability (from collection to initiation)

Room temperature: 2 days

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 

CPT Codes

88271x16, 88275x8

Available Stat

No

Test Code

Blood: BPAML
Bone marrow: PAML

Performing Lab

Cytogenetics

Performed

Mon - Fri, 9AM - 5PM

Methodology

FISH

Collect

Blood or bone marrow aspirate: Dark green top
Bone marrow core: Sterile container with medium

Sample Type

Blood or bone marrow

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.

Synonyms

  • PAML
  • BPAML

Stability (from collection to initiation)

Room temperature: 2 days

Reported

7-14 days

Reflex Testing

An  interpretation of this test by a laboratory physician will automatically be performed and billed for separately.

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 

CPT Codes

88271x16, 88275x8
Ordering

Available Stat

No

Performing Lab

Cytogenetics

Performed

Mon - Fri, 9AM - 5PM

Methodology

FISH

Reported

7-14 days

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 

Reflex Testing

An  interpretation of this test by a laboratory physician will automatically be performed and billed for separately.

Synonyms

  • PAML
  • BPAML
Collection

Sample Type

Blood or bone marrow

Collect

Blood or bone marrow aspirate: Dark green top
Bone marrow core: Sterile container with medium

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Stability (from collection to initiation)

Room temperature: 2 days

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.
Processing

Test Code

Blood: BPAML
Bone marrow: PAML

Performing Lab

Cytogenetics

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.

Stability (from collection to initiation)

Room temperature: 2 days
Result Interpretation

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 
Administrative

CPT Codes

88271x16, 88275x8
Complete View

Available Stat

No

Test Code

Blood: BPAML
Bone marrow: PAML

Performing Lab

Cytogenetics

Performed

Mon - Fri, 9AM - 5PM

Methodology

FISH

Collect

Blood or bone marrow aspirate: Dark green top
Bone marrow core: Sterile container with medium

Sample Type

Blood or bone marrow

Preferred Volume

Blood: 2 mL
Bone marrow aspirate: 2 mL
Bone marrow core: 2 cm

Minimum Volume

Blood: 1 mL
Bone marrow aspirate: 1 mL
Bone marrow core: 1 cm

Unacceptable Conditions

Clotted samples. Samples received refrigerated or frozen.

Synonyms

  • PAML
  • BPAML

Stability (from collection to initiation)

Room temperature: 2 days

Reported

7-14 days

Reflex Testing

An  interpretation of this test by a laboratory physician will automatically be performed and billed for separately.

Additional Information

Fluorescence In situ hybridization (FISH) is performed to detect deletion of 5q or loss of a chromosome 5, deletion of 7q or loss of a chromosome 7, PML/RARA gene fusion, RUNX1/RUNX1T1 gene fusion, CBFB/MYH11 gene fusion, MLL (11q23) rearrangement, NUP98 (11p15) rearrangement, and GLCBF/BGLCBF Translocation GLIS2/ CBFA2T3 16p13.3 and 16q24.3 fusion probe from pediatric samples.
 

CPT Codes

88271x16, 88275x8